| Message: | 1.17α-estradiol
CAS register number 57-91-0
EINECS 200-023-8
Molecular formula C18H24O2
Molecular weight 272.38
Assay 98%
Appearance White crystalline powder
Usage : Hormonal contraception; Hormone replacement therapy
Hormone replacement therapy in Male-To-Female Transsexuals
Blocking estrogens
Description:
Estradiol (called α- estradiol or 17α- estradiol) for human breast cancer cells in tissue culture biologically active estrogen. Not part of the 17- and selective estrogen receptor (ER-X) traditional hormone / receptor of the endocrine system, but an important autocrine / paracrine function of the system is part of the growth in the adult brain. In menopause, and neurodegenerative diseases (eg Alzheimer's disease and ischemic stroke) treatment, 17- estradiol may have important implications for hormone replacement therapy thing.
The development of secondary sex characteristics in women is driven by estrogens, to be specific, estradiol. These changes are initiated at the time of puberty, most are enhanced during the reproductive years, and become less pronounced with declining estradiol support after the menopause. Thus, estradiol enhances breast development, and is responsible for changes in the body shape, affecting bones, joints and fat deposition. Fat structure and skin composition are modified by estradiol.
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