| Message: | Tesamorelin, (formerly known as TH9507), is a type of peptide called a growth hormone-releasing factor (GHRF). GHRF causes growth hormone to be created and spread in the body, which helps increase metabolism, reduce belly fat, improve body shape, and use of energy.
Tesamorelin (formerly known as TH9507) is a synthetic growth hormone-releasing factor that stimulates the pituitary gland in the brain to secrete growth hormone; this indirect approach appears to maintain more stable, natural levels, like CJC-1295 DAC,. Clinical trials have shown that tesamorelin significantly reduces abdominal fat with fewer side effects than human growth hormone itself, although abdominal fat may return after the Tesamorlein is discontinued (depending upon the individual). Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals as well as similarly reducing abdominal fat in NON-HIV-Infected individuals.
Product Name: Tesamorelin
Molecular Formula: C221H366N72O67S
Molecular Weight: 5135.77794
PubChem: CID 44201342
Synonyms: Hex-hGRF, ThGRF(1-44), TH-9507, (Hexenoyl trans-3)-hGRF(1-44)-NH2
Prior to FDA approval, clinical studies were conducted on patients with HIV who had some fat accumulation and whose antiviral therapy was stable. Three studies of 816 patients showed that a daily treatment reduced abdominal fat after 26 weeks. Most patients experienced a reduction of approximately 18 percent. Abdominal fat began to accumulate again once the patients stopped treatment.
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