Message: | 1.Gliclazide
Another Name:
CAS:244-260-5
Molecular Weight:323.4105
Molecular Formula:C15H21N3O3S
The pharmacological effects of product is a second-generation sulfonylurea oral hypoglycemic agents hypoglycemic effect on normal subjects and patients with diabetes have. The hypoglycemic strength between tolbutamide and glibenclamide.This product is mainly the direct effect on the pancreas, to promote Ca transport to pancreatic β cells, stimulate insulin secretion. In the same time, but also can improve the surrounding tissue for glucose metabolism, thereby reducing blood sugar.
In addition, the product can inhibit platelet release of arachidonic acid from phospholipids, thereby reducing thromboxane (TXA3), synthesis, inhibition variety of coagulation factors (Ⅴ, VIII and XI), and increased plasmin plasminogen activator factor level, and promote the dissolution of fibrin. The animal studies also found that the product can reduce plasma cholesterol, triglyceride |