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1.(+)-Camptothecin |
Create: 07/25/2016 |
Expired Date: | 07/20/2022 |
Category: | Esters [Chemical] |
Message: | 1.(+)-Camptothecin Synonym: 1,6-DIHYDROXY-7-GLUCURONOSYLFLAVONE;(20S)-CAMPTOTHECIN;4-ETHYL-4-HYDROXY-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)DIONE;5,6-DIHYDROXY-7-GLUCURONOSYLFLAVONE;5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-1-BENZOPYRAN-7-YL BETA-D-GLUCOPYRANOSIDURONIC ACID;CAMPTOTHECIN, CAMPTOTHECA ACUMINATA;CAMPTOTHECINE;(+)-CAMPTOTHECIN CAS: 7689-03-4 EINECS: 444-280-6 Assay: NLT99% M.F: C20H16N2O4 M.W: 348.35 MP: 260 °C (dec.)(lit.) Density: 1.51 g/cm3 Appearance: Light yellow needle powders Application: Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent |
City: | Beijing Beijing[CN] |
Location: | |
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