| Message: | Exenatide Acetate
CAS
Exenatide, an incretin mimic peptide comprised of 39 amino acid residue, is a new antidiabetic drug approved by FDA in 2005 for the treatment of diabetes mellitus type 2.
The main physiological functions are followings: Promote insulin excretion in glucose-dependence manner, restoration of glucose sensitivity to the islets, inhibition of apoptosis of existing cells and increase the number of β Cells, inhibition of gastric emptying leads to decreased food intake and reduced body weight. The exenatide therapy has the following advantages to compare with insulin therapy: No hypoglycemia effect, reducing body weight, improving insulin resistance, promoting islets cell function of patients.
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