| Message: | Product Name: Leflunomide
Synonyms: LEFLUNOMIDE;HWA 486;ALPHA,ALPHA,ALPHA-TRIFLUORO-5-METHYL-4-ISOXAZOLECARBOXY-P-TOLUIDIDE;5-METHYLISOXAZOLE-4-(4-TRIFLUOROMETHYLCARBOXANILIDE);5-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-4-ISOXAZOLECARBOXAMIDE;N-(4-TRIFLUOROMETHYLPHENYL)-5-METHYLISOXAZOL-4-CARBOXAMIDE;5-methylisoxazole-4-carboxylicacid(4-trifluoromethyl)anilide;5-methyl-n-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamid
CAS: 75706-12-6
MF: C12H9F3N2O2
MW: 270.21
Product Categories: Active Pharmaceutical Ingredients;API;Osteoarthritis and Rheumatoid Arthritis;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Aromatics;Heterocycles;An immunosuppressive agent;CARDENE;Other APIs
mp 163-168°C
storage temp. 2-8°C
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Chemical Properties Off White Crystalline Solid
Usage An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutical
Usage vasodilator
Usage anti-Altzheimer therapeutic. |
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