Message: | 1. Quick Detail:
Megestrol acetate
Synonyms: Nomegestrol Acetate; 17-hydroxy-6-methylpregna-4
Inchi: InChI=1/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23, 15(2)25)28-16(3)26/h12-13, 18-20H, 6-11H2, 1-5H3/t18-, 19+, 20+, 22-, 23+, 24+/m1/s1
CAS No.: 595-33-5
ECNECS No.: 209-864-5
MF: C24H32O4
MW: 384.5
Purity: 99%
Density: 1.15g/cm3
Melting Point: 214º C
Boiling Point: 507.1° Cat760mmHg
Refractive Index: 11 ° (C=2, CHCl3)
Flash Point: 218.5° C
Appearance: White or light yellow crystalline powder
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Lead time: Within 12 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage: 1. Mainly used for short-acting oral contraceptives, also can be used for intramuscular injection of long-acting contraceptives. 2. For the treatment of dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinoma
2. Product description:
Megestrol acetate, also known as 17α -acetoxy-6-dehydro-6-methylprogesterone, and sometimes abbreviated as MGA or MA, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.
3. Application:
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
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