| Message: | Bifidobacterium longum lysate
CAS:96507-89-0
EINECS:306-168-4
Probiotic health benefits
As an important organism involved in the maintenance of the human gastrointestinal tract, B. longum is commonly used as a probiotic in various dairy products.Its presence has been associated with many health benefits including improving lactose tolerance and preventing diarrhea, food allergies, and colonization by pathogens.Some strains of B. longum were demonstrated to have an antioxidative effect by inhibiting linoleic acid peroxidation,a process that results in the creation of lipid hydroperoxides that decompose into highly reactive radicals associated with aging and age-related diseases.Additionally, B. longum can scavenge free radicals, lowering a person’s chance of atherosclerosis and stroke.The ability of B. longum to remove cholesterol from its environment by incorporating cholesterol into its membrane is thought to lower the serum cholesterol level in humans.
Therapeutic uses
Cancer treatment
As an anaerobe, B. longum is able to localize and proliferate in the hypoxic regions of solid tumors when injected intravenously.It is proposed that by introducing genes into B. longum that generate anti-tumor enzymes, B. longum will be able to act as the vector in cancer gene therapy.B. longum is an ideal vector as its actions should remain tumor-specific, it is non-pathogenic, and it generally easily killed by antibiotics unlike other potential anaerobic vectors such as Salmonella or Clostridium.
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