| Message: | Weight Loss Steroids White Pharmaceutical Intermediates Powder Rimonabant Hydrochloride For Fat Loss And Body Shaper
1. Quick Detail:
product name Rimonabant hydrochloride
Alias RIMONABANT HCL;Rimonabant(Acomplia)
CAS 158681-13-1
Molecular Formula C22H21Cl3N4O.ClH
Molecular Weight 500.25
Appearances white or off white solid
Usage pharmaceutical intermediates
2. Description:
Rimonabant hydrochloride (SR-141716A) is a potent and selective CB1 cannabinoid inverse agonist/antagonist with a Ki of 1.6 nM, minimal affinity for CB2, and and some GPR55 agonist activity. Rimonabant was developed as an anti-obesity drug because of its appetite suppressant activity, but was taken off the market because of side effects of depression and anxiety.
Under development by Sanofi-Aventis, Acomplia (rimonabant) is a selective CB1 endocannabinoid receptor antagonist indicated for the treatment of obesity.
It works by blocking endogenous cannabinoid binding to neuronal CB1 receptors. Activation of these receptors by endoegenous cannabinoids, such as anadamide, increases appetite. It is the most advanced endocannabinoid receptor antagonist in clinical development and offers a novel therapeutic approach to appetite control and weight reduction.
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