| Message: | CAS NO.: 171596-29-5
Assay: 98%
Molecular Formula:C22H19N3O4
Molecular Weight:389.341
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Description: White Crystalline Powder
Storage: Shading, Confined Preservation
Action principle: tadalafil is cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective, reversible inhibitor, when stimulation caused local release of nitric oxide, PDE5 received tadalafil suppression, to improve the level of * * in the cavernous body of cGMP, which leads to smooth muscle relaxation, blood flows into the police organization, such as sexual stimulation produces an erection. And he Dalafeibu work. Preclinical data indicate that tadalafil no particular harm to human body.
Absorption: after oral administration of tadalafil in rapid absorption, 2 hours to reach the average maximum observed plasma concentration time after taking place in (Cmax). The effect of absorption rate and extent of food was not the tadalafil, so this right with or not with food and clothing. Medication time (morning or night) had no effect on the rate and extent of absorption.
Distribution: the average volume of distribution of about 63 liters, that tadalafil distribution into tissues. In the treatment, plasma concentration within 94% of tadalafil and protein binding. Protein binding is not affected by the impairment of renal function |
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