| Message: | Alias: PEG-Suc-YQPPSTNKNTKSQ(d)R(d)RKGSTFEEHK-NH2;
M.F.: C121H200N42O39
Purity (HPLC): 98.0%
Single Impurity(HPLC): 0.5%max.
Amino Acid Composition: about 10% of theoretical
Peptide Content(N%): 80.0%min.
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Bacterial Endotoxins: 5 EU/mg max.
Appearance: White powder
Water Content(Karl Fischer): 8.0%max.
Acetate Content(HPLC):10.0%max.
Specific Rotation: (20/D) -55.0 ~ -65.0 dgree(c=1 1%HAc)
Description;
1.MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes.
2.PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down.
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