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Estriol
Synonyms:TRIDESTRIN;(16-alpha,17-beta)-estra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol;(16-alpha,17-beta)-oestra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol;1,3,5-estratriene-3-beta,16-alpha,17-beta-triol;1,3,5-Estratriene-3beta,16-alpha,17-beta-triol;1,3,5-oestratriene-3-beta,16-alpha,17-beta-triol
CAS:50-27-1
EINECS:200-022-2
MF:C18H24O3
MW:288.38
Assay: 97.0%-102.0%, USP30.
Character: White crystalline powder.
Melting point :280-282 ° C (lit.)
Refractive index: 58 ° (C = 0.4, Dioxane)
Storage conditions :-20 ° C Freezer
Chemical Properties white crystalline powder. Mp283 ℃; relative density 1.27; Specific rotation [α] 25D +34.4 ° (pyridine), 25D +58 ° ± 5 ° (4%, dioxane); ethanol solution at a maximum absorption wavelength of 280nm. The crystal is insoluble in water, slightly soluble in ethanol (1:500), ether, chloroform, dioxane, and vegetable oils, soluble in pyridine and alkali hydroxide solution.
Use of estrogen drugs. For neutropenia, a variety of menstrual, senile vaginitis, menopausal syndrome. May have a temporary swelling and lumps in the breast, menstrual cycle disorders, around January after stopping self-healing. There breast hyperplasia, breast lumps, and female hormones may tumors, aplastic anemia and liver disease hanged. For the treatment of leukopenia, on an enlarged prostate, prostate cancer have a certain effect
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