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Alias:hexadecadrol,Dexamethasonum,DXM
CAS: 50-02-2
EINECS:200-003-9
MF:C22H29FO5
MW: 414.62
Purity: 99%
Melting point: 262-264 °C(lit.)
Appearance: white crystalline powder
Use:Mainly anti-inflammatory, antivirus, allergy, anti-rheumatism, clinical is used more widely.
Application: A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase
Dexamethasone is a type of steroid medication.It is used in the treatment of rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis, among others.In adrenocortical insufficiency it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone.In preterm labor it may be used to improve outcomes in the baby.It maybe taken by mouth, as an injection into a muscle, or intravenously.The effects of dexamethasone is frequently seen within a day and lasts for about three days.
The long term use of dexamethasone may result in thrush, bone loss, cataracts, easy bruising, or muscle weakness.It is pregnancy category C in the United States and class A in Australia, meaning it has been frequently used in pregnancy and not been found to cause problems to the baby.It should not be taken when breastfeeding.Dexamethasone has anti-inflammatory and immunosuppressant effects.
Dexamethasone was first made in 1957.It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.Dexamethasone is not expensive.In the United States a month of medication typically costs less than 25 USD.In India a course of treatment for preterm labor is about 0.5 USD.It is available in most areas of the world. |