| Message: | Product Name: Tetracaine HCl
Alias: Tetracaine Hydrochloride,Pontocaine
CAS: 136-47-0
EINECS: 205-248-5
MF: C15H25ClN2O2
MW: 300.82
Assay: 99%
Melting Point: 149℃
Grade: Pharmaceutical Grade
Storage: Closed, confined and shading preservation
Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
Catergory: API intermediates;local anesthetic;Sodium channel;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;pharmaceutical raw material;cytobiology
Description
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Application
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
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