| Message: | Follistatin 344/sherry@chembj.com
Product Name: Follistatin 344
Alias: FST
Specification: 1mg/vial
Grade: Reagent Grade
Appearance: White To Off-White Crystalline Powder Or Lumps
Follistatin Benefits
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene. Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin.Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.
Functional Mechanism
An earlier name for the same protein was FSH-suppressing protein (FSP). At the time of its initial isolation from follicular fluid, it was found to inhibit the anterior pituitary's secretion of follicle-stimulating hormone (FSH).
Follistatin works by binding to and inhibiting transforming TGF-β peptides such as myostatin which is responsible for regulating and limiting muscle growth. It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.
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