| Message: | MGF/sherry@chembj.com
Product Name: Mechano Growth Factor,MGF
Molecular Formula: C121H200N42O39
Molecular Weight: 2888.16
Purity: 99%
Specification: 2mg/vial
Grade: Pharmarceutical Grade
Appearance: White Lyophilized Powder
2 Kinds Of MGF Splice Variants Of IGF
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. It's called MGF as IGF-IEa is a bit of a mouthful and harder to identify amongst the other IGF variants.
IGF-1Ec:This is the first phase release igf splice variant and it appears to stimulate satellite cells into activation, This is the closest variant to synthetic MGF.When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis.
IGF-1Ea:After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. It is the secondary release of igf from the liver, and its far less anabolic and shorter acting.
The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.
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