| Message: | CAS 797-63-7 Levonorgestrel/sherry@chembj.com
Product Name: Levonorgestrel
Other Name: l-norgestrel,D-norgestrel
CAS: 797-63-7
EINECS: 212-349-8
MF: C21H28O2
MW: 312.45
Appearance: White Or Almost White Crystalline Powder
Levonorgestrel (or l-norgestrel or D-norgestrel) (Plan B, Next Choice, Postinor, "the morning after pill", and others) is a second generation progestin (synthetic progestogen) used as an active ingredient in some hormonal contraceptives, includingcombined oral contraceptive pills, progestogen only pills, emergency contraceptive pills, intrauterine systems, contraceptive implants, and hormone replacement therapy.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basichealth system.
Oral Contraception
At low doses, levonorgestrel is used in monophasicand triphasicformulations of combined oral contraceptive pills, with available monophasic doses ranging from 100-250μg, and triphasic doses of 50μg/75μg/125μg.
At very low daily dose of 30μg, levonorgestrel is used in some progestogen only pillformulations.
Emergency Contraception
Levonorgestrel is used in emergency contraceptive pills(ECPs), both in a combined Yuzpe regimenwhich includes estrogen, and as a levonorgestrel-only method. The levonorgestrel-only method uses levonorgestrel 1.5mg (as a single dose or as two 0.75mg doses 12 hours apart) taken within 3 days of unprotected sex, with one study indicating that beginning as late as 120 hours (5 days) after intercourse could be effective.
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