| Message: | CAS 145-13-1 Pregnenolone/sherry@chembj.com
Product Name: Pregnenolone
CAS: 145-13-1
EINECS: 205-647-4
MF: C21H32O2
MW: 316.48
MP: 188-190℃
alpha: 28.5 o (c=1, EtOH)
Storage Temp: Refrigerator
Categories: Steroids;Steroids&Hormones, Pharmaceuticals
Usage: Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.
Pregnenolone (3β-hydroxypregn-5-en-20-one), also known as P5, is an endogenous steroid hormone. It is the precursor of the progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.
Like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. It contains ketone and hydroxyl functional groups, two methyl branches, and a double bond at C5, in the B cyclic hydrocarbon ring. Like many steroid hormones, it is hydrophobic. Its esterified version, pregnenolone sulfate, is water-soluble.
Pregnenolone undergoes further steroid metabolism in one of three ways.
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