Message: | CAS 1264-62-6 Erythromycin Ethylsuccinate/sherry@chembj.com
Product Name: Erythromycin Ethylsuccinate
Alias: Erythromycinethyl Succinate,Erythroped,Erythrocin Ethyl Succinate,Sigapedil
CAS: 1264-62-6
EINECS: 215-033-8
MF: C43H75NO16
MW: 862.05
Grade: Pharmaceutical Grade
Appearance: White Crystalline Powder
Erythromycin is produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids. The base, the stearate salt, and the esters are poorly soluble in water. Erythromycin ethylsuccinate is an ester of erythromycin suitable for oral administration. Erythromycin ethylsuccinate is known chemically as erythromycin 2'-(ethylsuccinate).
Erythromycin is easily inactivated by gastric acid; therefore, all orally administered formulations are given as either enteric-coated or more-stable salts or esters, such as erythromycin ethylsuccinate. Erythromycin is very rapidly absorbed, and diffuses into most tissues and phagocytes. Due to the high concentration in phagocytes, erythromycin is actively transported to the site of infection, where, during active phagocytosis, large concentrations of erythromycin are released.
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