| Message: | CAS 859-18-7 Lincomycin HCL/sherry@chembj.com
Product Name: Lincomycin HCl
Alias: Lincocin,Lincorex,Lincomycin Hydrochloride Monohydrate
CAS: 859-18-7
EINECS: 212-726-7
MF: C18H34N2O6S.HCl
MW: 443.00
Grade: Pharmaceutical Grade
Appearance: White Crystalline Powder
Lincomycin is a lincosamide antibiotic that comes from the actinomyces Streptomyces lincolnensis.A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality.
Although similar in structure, antibacterial spectrum, and mechanism of action to macrolides, lincomycin is also effective against other organisms including actinomycetes, mycoplasma, and some species of Plasmodium.
However, because of its adverse effects and toxicity, it is rarely used today and reserved for patients allergic to penicillin or where bacteria have developed resistance.
Lincomycin is an injectable man-made antibiotic. Lincomycin kills bacteria by interfering with the ability of bacteria to produce important proteins necessary for them to survive. Lincomycin is effective against many types of bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Propionibacterium acnes, and others.
Lincomycin is used for treating serious bacterial infections caused by susceptible strains of streptococci, pneumococci, and staphylococci. Use of lincomycin is reserved for penicillin-allergic patients or when penicillin-based treatment is not appropriate. This antibiotic should only be used to treat serious infections because of rare but sometimes fatal intestinal problems have occurred. |
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