| Message: | CAS 1218-35-5 Xylometazoline HCl/sherry@chembj.com
Product Name: Xylometazoline HCl
Alias: Xylometazoline hydrochloride
CAS: 1218-35-5
EINECS: 214-936-4
MF: C16H25ClN2
MW: 280.8361
Assay: 99%
Boiling Point: 394.2 ° C at 760 mmHg
Flash Point: 192.2 ° C
Vapor Pressure: 4.56E-06mmHg at 25 ° C
Appearance: White Powder
Description
Xylometazoline (Pronunciation: Zylow-met-TAH-zoleen), also known as xylomethazoline, is a drug which is used as a topical nasal decongestant.It is applied directly into the nose, either as a spray or as drops.
Xylometazoline is marketed under many brand names (see below) but the most common by far is Otrivine. The standard adult solution strength is 0.1% w/V xylometazoline, and the dose for children under 12 is usually 0.05%.
It should not be used for too long a period of time, or rebound effect may occur after discontinuation (see: Rhinitis medicamentosa). It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Specification
Molecular Weight: 280.84
Molecular Formula: C16H24N2.HCl
Applications
Allergy (hypersensitivity) to xylometazoline or any of the other ingredients
People who have undergone neurosurgery
People who are taking or who have taken drugs for depression called monoamine oxidase inhibitors within the previous 2 weeks
People taking other similar decongestants
Heart problems
Problems with blood circulation
High blood pressure (hypertension)
Overactive thyroid (hyperthyroidism)
People taking beta-blockers, which are used for high blood pressure (hypertension)
Inflammation of the skin or nose
People who have had their pituitary gland removed by surgery
Children under 12 years of age
Cancer of the adrenal gland (phaeochromocytoma)
A type of eye disease with increased pressure inside the eye called closed-angle glaucoma
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