| Message: | CAS 63-42-3 Lactose/sherry@chembj.com
Product Name: Lactose
Alias: Lactin,Lactobiose,Lactosum
CAS: 63-42-3
EINECS: 200-559-2
MF: C12H22O11
MW: 342.30
Assay: 99.0%min
Specifications: 80 mesh,100 mesh, 200 mesh
Grade: Pharmaceutical Grade,Food Grade
Appearance: White Or Almost White Crystalline Powder
Lactose is added to pills as a filler because of its physical properties and low price. For similar reasons it can be used to dilute heroin.It is a very good binder / filler because of its compressibility, flow and high solubility.
General Properties Of Lactose As An Excipient
Lactose is widely used as a filler or filler-binder in the manufacture of pharmaceutical tablets and capsules. The general properties of lactose that contribute to its popularity as an excipient are its:
Cost Effectiveness;
Availability;
Bland taste;
Low hygroscopicity;
Compatibility with active ingredients and other excipients;
Excellent physical and chemical stability;
Water solubility
Various lactose grades are commercially available that have different physical properties, such as particle size distribution and flow characteristics. The most common form of lactose used in pharmaceutical formulation is crystalline a-lactose monohydrate. This form is available in a range of milled and sifted pharmaceutical grades differing in physical properties, such as flowability, bulk density, and particle size distribution.
Lactose is also available in modified forms for use as a filler-binder in the production of tablets by the direct compression method. The two most important forms for this application are spray dried lactose and anhydrous lactose (Figure 3). These forms have the key property that they are inherently compactable, that is, they are able to form a solid compact (ie, tablet) under compression.
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