Message: | MF:C17H19N5
MW:293.37
MP:81-82ºC
Assay:98%~102%
Appearance:White crystalline powder
Active life cycle:6 hours
Grade:Pharmaceutical Grade
Storage:Shading, confined preservation
Key words:Anastrozole Arimidex 120511-73-1 anti-estrogen breast cancer
Usage :
Anastrozole is a potent non-steroidal aromatase inhibitors , which lead the decrease of plasma level of estrogen, inhibited the growth of breast cancer. For the treatment of advanced breast cancer in postmenopausal women patients.
Description :
Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer.
Many breast cancers also contain aromatase; the importance of tumor-generated estrogens is uncertain. Treatment of breast cancer has included efforts to decrease estrogen levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed progression of tumor growth in some women. Anastrozole is a potent and selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone.
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