my account  log out
 

Anti-CD24 immunotoxin SWA11 (IgG)-PE

Create: 02/27/2017
Expired Date:02/22/2023
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This immunotoxin was achieved by conjugating/fusing the Anti-CD24 monoclonal antibody to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to CD24-expressing colorectal cancer (CRC) cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating colorectal cancer.
City:Shirley[US] 
Location:
 
Feb 01 2023 VBS++ (with Ca and Mg) Buffer270
Feb 01 2023 GVBE Buffer278
Feb 01 2023 GVB++ (with Ca and Mg) Buffer278
Feb 01 2023 Hemolysin (Rabbit Anti-Sheep Cell Hemolysin)273
Aug 30 2019Anti-HSV-2 gH Antibody463
Aug 30 2019Anti-L. major LPG Antibody545
Aug 30 2019Anti-DENV-1 Antibody453
Aug 30 2019Anti-BPV-1 L1 Antibody467
Aug 30 2019Anti-H3N2 HA Antibody455
Aug 30 2019Anti-EIAV env Antibody476

return back

Copyright © toextrade Inc. All rights reserved. Contact us