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Anti-CD24 immunotoxin SWA11 (IgG)-RTA

Create: 02/27/2017
Expired Date:02/17/2021
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This immunotoxin was achieved by conjugating/fusing the Anti-CD24 monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to CD24-expressing colorectal cancer (CRC) cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of colorectal cancer.
City:Shirley[US] 
Location:
 
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