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Anti-CD38 immunotoxin IB4 (IgG)-Gel

Create: 02/27/2017
Expired Date:02/24/2021
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This immunotoxin was achieved by conjugating/fusing the Anti-CD38 monoclonal antibody to gelonin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to CD38+ cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then, gelonin, like abrin and ricin, inhibits protein synthesis by damaging the 60S subunit of mammalian ribosomes. It was designed for treating Non Hodgkin lymphoma (NHL).
City:Shirley[US] 
Location:
 
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