| Message: | Raw Material 16alpha-Hydroxyprednisolone
Product Name: 16alpha-Hydroxyprednisolone
CAS: 13951-70-7
EINECS: 237-731-1
MF: C21H28O6
MW: 376.45
Assay: 98%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Melting Point: 235-238 dec.
Density: 1.381 g/cm3
Flash Point: 325.6 dec.
Storage: Keep it under seal in cool and dark place
Boiling Point: 591.5 dec. at 760 mmHg
16alpha-hydroxyprednisolone is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17a position. This step is performed by the mitochondrial cytochrome P450 enzyme 17a-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy. 16alpha-Hydroxyprednisolone is also an advanced intermediate in the synthesis of various corticosteroids such as budesonide and ciclesonide.
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