Message: | Pharmaceutical Intermediate Phenyl Salicylate
Product Name: Phenyl Salicylate
CAS: 118-55-8
EINECS: 204-259-2
MF: C13H10O3
MW: 214.22
Purity: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Melting Point: 41.5 dec.
Boiling Point: 306.6 dec.at 760 mmHg
Solubility: Water: 1 g/6670 mL
Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It can be created by heating salicylic acid with phenol. Once used in sunscreens, phenyl salicylate is now used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes.It is also used frequently in school laboratory demonstrations on how cooling rates affect crystal size in igneous rocks.
In the salol reaction, phenyl salicylate reacts with o-toluidine in 1,2,4-trichlorobenzene at elevated temperatures to the corresponding amide o-Salicylotoluide. Salicylamides are one type of drug.
It has been used as an antiseptic based on the antibacterial activity upon hydrolysis in the small intestine.It acts as a mild analgesic. |