| Message: | Raw Biochemical Material Succimer
Product Name: Succimer
Alias: Meso-2,3-Dimercaptosuccinic Acid;DMSA;Dimercaptosuccinic Acid;2,3-Dimercaptosuccinic Acid
CAS: 304-55-2
MF: C4H6O4S2
MW: 182.22
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Application: Used as antidotes of heavy metal and health protection medication
Dimercaptosuccinic acid (DMSA), is the organosulfur compound with the formula HO2CCH(SH)CH(SH)CO2H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour. It occurs in two diastereomers, meso and the chiral dl forms. The meso isomer is used as a chelating agent. The acid is most often used as a treatment for heavy metal toxicity, and is a water-soluble and non-toxic substance.
Dimercaptosuccinic acid (CHEMET) is indicated for the treatment of lead poisoning in children with blood level measured above 45 μg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMSA can cross the blood-brain barrier of mice,but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.
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