Message: | Clomiphene Citrateis a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, putsClomiphene Citratein a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. As for women, the only real use for Clomiphene Citrate is the possible management of endogenous estrogen levels near contest time. This can increase fat loss and muscularity, particularly in female trouble areas such as this HIPS and thighs. Clomiphene Citrate however often produces troubling side effects in women (discussed below), and is likewise not in very high demand among this group of athletes. Clomid are also occasionally used periodically during a steroid cycle, in an effort to prevent natural testosterone levels from diminishing. In many instances this practice can prove difficult however, especially when using strong androgens for longer periods of time. |