Message: | Neomycin sulfate
CAS: 1405-10-3
MF: C23H48N6O17S
MW: 712.72
EINECS: 215-773-1
MP >187° C (DEC. )
Refractive index 56 ° (C=10, H2O)
Storage temp. 2-8° C
Solubility H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8° C. Stable at 37° C for 5 days.
Chemical Properties White powder.
Usage antibacterial
Usage Neomycin is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
Detail description:
Neomycin Sulfate Tablets, USP, for oral administration, contain neomycin which is an antibiotic obtained from the metabolic products of the actinomycete Streptomyces fradiae. It has the following molecular formula: C23H46N6O. 2? H2SO4 with a molecular weight of 614.67.
Chemically, it is O-2, 6-diamino-2, 6-dideoxy-a -D- glucopyranosyl(1? 3)-O-b-D- ribofuranosyl-(1? 5) O-[2, 6-diamino-2, 6-dideoxy-a-D-glucopyranosyl-(1? 4)]-2-deoxy-D-streptamine. Neomycin B is identical except that the a- D- glucopyranosyl residue in the neobiosamine moiety is b-L-idopyranosyl.
|