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Bispecific PD-1/CD3 BiTE

Create: 04/24/2017
Expired Date:04/10/2025
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
City:Shirley, NY[US] 
Location:
 
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