| Message: | 1.Hexarelin
2.Sequence: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
3.Molecular formula: C47H58N12O6
4.MW : 887.04022
5.CAS number: 140703-51-1
6.Brand:QA
7.PubChem: CID 5464109
8.Synonyms: Hexarelin Acetate, HEX, Examorelin
9.HS Code : 2937190090
10.Appearance : White Powder
11 .Purity : 98%
12 .Grade : Pharmaceutical Grade
13.Storage: Closed, below 2 ~ 8oC preservation
14.Usage : A synthetic can promote GH release six peptide, clinically used in the treatment of secretion deficiency ; HEX Examorelin For Fat Loss & Cutting Cycles
15..Manufacturer :SiMeiQuan
16.Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
17.Storage:a cool(2~8 oC) & dry place protected from light, keep package close when not in use.
Application:
Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion by the pituitary gland. The pathway activated by binding of ghrelin to the secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems. One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis. |
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