Native Mammalian Ubiquitin Conjugating Enzyme Fractions

Create: 07/13/2017

Expired Date:	never
Category:	Ligases [Chemical]
Message:	Ubiquitin-conjugating enzymes perform the second step in the ubiquitination reaction that targets a protein for degradation via the proteasome. The ubiquitination process covalently attaches ubiquitin, a short protein of 76 amino acids, to a lysine residue on the target protein. Once a protein has been tagged with one ubiquitin molecule, additional rounds of ubiquitination form a polyubiquitin chain that is recognized by the proteasome's 19S regulatory particle, triggering the ATP-dependent unfolding of the target protein that allows passage into the proteasome's 20S core particle, where proteases degrade the target into short peptide fragments for recycling by the cell. http://www.creative-enzymes.com/product/Native-Mammalian-Ubiquitin-Conjugating-Enzyme-Fractions_1578.html





City:	Shirley[US]
Location:

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