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Native Proteus vulgaris Chondroitinase ABC |
Create: 08/13/2017 |
Expired Date: | never |
Category: | Lyases [Chemical] |
Message: | Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl or (1-3)-α-L-iduronosyl linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate, and acts slowly on hyaluronate. The molecular weight is found to be approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is found to be 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid and tempeRature optimum is 37°C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activator of the enzyme. http://www.creative-enzymes.com/product/Native-Proteus-Vulgaris-Chondroitinase-ABC_1104.html |
City: | Shirley[US] |
Location: | |
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