| Message: | Product Name: Chlormadinone Acetate
CAS:302-22-7
Molecular Formula C23H29ClO4
Molecular Weight 404.93
EINECS: 206-118-0
mp: 212°C
Appearence: white crystalline powder
Usage: Orally active progesteron with antiandrogenic activity; has been used in combinations as an oral contraceptive. Progestogen; antineoplastic (hormonal)
Application:
Chlormadinone acetate is a steroidal progestin with additional antiandrogen andantigonadotropic (and thus also antiestrogenic) effects. It is used clinically as a hormonal contraceptive, and in part due to its lowering of estrogen levels, but also for improved effectiveness in contraception, chlormadinone is frequently combinedwith ethinyl estradiol for this purpose.
Chlormadinone acetate has a strong anti-gonadotropic effect, through negative feedback on gonadotropin secretion, and has been used for more than 20 years alone for contraception in arterial risk patients. The clinical and metabolic tolerability of CMA has been demonstrated in numerous clinical studies with duration of treatment of up to 2.5 years.
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