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Anti-ERBB2 (Trastuzumab-LC-Q147)-DBCO-MMAF ADC

Create: 09/27/2017
Expired Date:never
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This ADC product is comprised of an anti-ERBB2 monoclonal antibody (Trastuzumab variant,LC-Q147) conjugated via a DBCO linker to MMAF. The MMAF is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAF binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-erbb2-37.htm
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