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Product Name:Ace-031
Unit Size:1mg/Vial
Appearance:Lyophilized Powder
Trademark:Quanao
Content:99%
HS Code:79674545
Physical State:White Powder
Storage:Below -18c
Synonyms:Acvr2b, Activin Receptor Type Iib
Export Markets:Global
Usage:Bodybuilding ;Myostatin Blockers
Product Description:
ACVR2B (ACE-031) body-building Purity:98% Activin Receptor Type IIB
ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes.
ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.
ACE-031 belongs to class of proteins of TGF-beta super family that regulate muscle growth. ACE-031 acts on the molecular switches of these molecules and promote muscle growth. In experimental studies, ACE-031 promotes muscle growth and inhibits ActRIIB receptor signaling. In pre-clinical studies, administration of ACE-031 for two weeks increased skeletal muscle density, decreased leptin levels, and increased adiponectin. |
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