| Message: | Melanoma drug Dabrafenib /Email:phoebe@chembj.com
Product Name: Dabrafenib (GSK2118436)
Synonyms: Dabrafenib;N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(tert-butyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;Dabrafenib free base(GSK2118436A);Dabrafenib (GSK2118436);GSK2118436A;Dabrafenib (GSK2118436A);Dabrafenib KB-57246;Debrafenib API
CAS: 1195765-45-7
MF: C23H20F3N5O2S2
MW: 519.5624096
Product Categories: Raf B protein kinase inhibitor;inhibitor;MAPK
density 1.443
Usage : Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM in cell-free assays, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.
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