| Message: | Product name :Rimonaban
Synonyms: ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716);5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide;A 281;Sr 141716
CAS: 168273-06-1
MF: C22H21Cl3N4O
MW: 463.79
Product Categories: Weight Loss;SR141716
Mol File: 168273-06-1.mol
Usage: Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane ; Mainly used for weight loss .
Product description:
Rimonabant is a weight loss drug, Sanofi-Aventis by the French company successfully developed for the treatment of obesity is the first cannabinoid type 1 receptor (CB1) antagonist, by selectively blocking the EC system cannabis Su -1 (cannabinoid-1, CB1) receptors play a role, can significantly reduce weight, reduce waist circumference, reducing risk factors for cardiovascular disease, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for the existence of clinical obesity or heart disease risk for people.
Application :
Rimonabant for the new weight-loss drug, can be applied to smoking cessation. A new weight-loss drug rimonabant (Rimonabant), not only can lose weight, but also lower blood pressure, cholesterol and blood sugar, domestically year clinical study found that subjects taking one to two months later, weight Save an average of six to eight kilograms. |
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