| Message: | CAS 170851-70-4 Ipamorelin
Product Name :Ipamorelin
CAS: 170851-70-4
Molecular Formula: C38H49N9O5
MW:711.853
Appearance: White powder
Grade : Pharmaceutical Grade
Purity:99%min
Specification:2mg/vial
Ipamorelin is a kind of GHRP
Ipamorelin is a peptidic, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.
Ipamorelin or NNC 26-0161, a polypeptide hormone, is a growth hormone secretagogue and ghrelin mimetic and analog. Ipamorelin belongs to the most recent generation of GHRPs and causes significant release of growth hormone by itself, due both to its suppression of somatostatin (an antagonist to GHRH) and stimulation of release of GH from the anterior pituitary, similar to GHRP-2 and GHRP-6 which are compounds from the same class (growth hormone releasing peptides). The cells that produce and release GH are known as somatotropes. Ipamorelin acts synergistically when applied during a native GHRH (growth-hormone releasing hormone) pulse or when co-administered with GHRH or a GHRH analog such as Sermorelin or GRF 1-29 (growth releasing factor, aminos 1-29).
The synergy comes both due to the suppression of somatostatin and the fact that ipamorelin increases GH release per-somatotrope, while GHRH increases the number of somatotropes releasing GH. There is also a secondary effect of neuronal excitation in the hypothalamus caused by ipamorelin, which lasts for approximately 3 hours after application, similar to GHRP-2 and GHRP-6.
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