| Message: | Product Name: Toremifene citrate
Synonyms: Fareston
CAS: 89778-27-8
MF: C32H36ClNO8
MW: 598.08
mp: 160-162°C
bp: 146-148°C
density: 1.045g/cm
refractive index: 1.416-1.418
storage temp: -20°C Freezer
half Life : around 5 days
appearance: white to Off-White Solid
Application:
Toremifene citrate is an oral selective estrogen receptor modulator (SERM) derived from triphenylethylene. It is FDA approved for breast cancer treatment, and has possible medical uses for prostate cancer. Bodybuilders will use this drug to combat gynecomastia (bitch tits), but it's still very new to the scene and has some drawbacks.
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body. As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
Toremifene is also agonistic to Estrogen receptors in other tissues in the body. This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.
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