| Message: | Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. PT-141, bremelanotide is experimental and is used for the purpose of sexual arousal. It is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger.
PT-141 (Bremelanotide) is that the 1st of a replacement category of medicine referred to as melanocortin agonists being developed to treat sexual pathology. The mechanism of action of PT-141 (Bremelanotide) could provide important safety and effectualness edges over presently obtainable product as a result of it acts on the pathway that controls sexual operate while not acting directly on the system. Clinical information indicates that PT-141 (Bremelanotide) could also be effective in treating a broad vary of patients tormented by impotence. The nasal formulation of PT-141 (Bremelanotide) being developed is as convenient as oral treatments, is a lot of patient-friendly than invasive treatments for impotence, like injections and trans-urethral pellets, and seems to lead to a fast onset of action.
Application:
PT-141 functions by activating the melanocortin receptor and MC4R namely. Bremelanotide originally was tested for nasal spray delivery but was discontinued after concerns about side effects. Bremelanotide PT141, as Melanotan II, may cause spontaneous arousal enhancing effect. Unlike other supplements, PT-141 results do not act on the vascular body, but directly increases desires through the nervous system .
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