| Message: | Name: Gonadorelin
Name: LH-RH, human, Gonadoreline;Gonadorelin Acetate
Peptide Sequen :Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
CAS No.: 71447-49-9; 33515-09-2
Molecular Formula: C59H83N17O17
Molecular Weight: 1302.39
Product Categories:Amino Acid Derivatives;Peptide;API;peptides
Appearance: White powder
Purity (HPLC): 98.0%min.
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤8.0%
Acetate Content(HPIC): ≤10.0%
Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)
MS (ESI): Consistent
Mass Balance: 95.0~105.0%
Gonadorelin Application:
Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use. |
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