| Message: | How to use Melanotan II for prosexual effect
Where there is no physical erectile dysfunction and where at least some degree of psychological libido exists, Melanotan II can greatly increase the tendency to penile erection. The situation can even become like the years of puberty, where scarcely even the beginning of a sexual thought or even nothing at all (perhaps an unconscious thought however) produces an erection. General physical fatigue can become irrelevant. These effects will not occur for all individuals, but do occur for many.
Prosexual usage requires injection at least about 4-6 hours prior to desired effect. Duration of action can be about 6-12 hours after onset of effect.
Needed dosage is typically about 1 mg, but for some even 0.5 mg can be effective. As a guide, dosage should not exceed 2 mg.
Because of the associated effect in increasing tendency to tan, frequency of MT-II use for this purpose is generally limited. If wishing this effect frequently, a better choice is to use PT-141 (bremelanotide,) an MT-II derivative.
Pharmacological class of Melanotan II:
Melanotan II is in the class of alphamelanocyte-stimulating hormone (alpha-MSH) mimetics. Alpha-MSH is produced in the pituitary, and activates alpha-melanocyte receptors. MT-II works in the same way.
There are a number of subtypes of alpha-melanocyte receptors (MC1-5.) Melanotan II is generally non-selective and activates multiple types. Activation of the MC1 receptor promotes skin pigmentation, while activation of the MC4 receptor can enhance tendency to penile erection.
For comparison, PT-141 is selective for the MC4 receptor and therefore promotes penile erection while having little or no effect on skin pigmentation. |
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