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Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (384)

Create: 07/23/2018
Expired Date:never
Category: Diagnostic equipment [Health&Medical&Pharmaceutical]
Message:L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of L-Trp that have immunosuppressive functions. Indoleamine 2,3- dioxygenases (IDO1 & IDO2), two of the rate limiting enzymes in this pathway, are upregulated in many tumors, providing cancer cells with an avenue for immune evasion. https://www.creativebiomart.net/human-ido1-fluorogenic-inhibitor-screening-assay-kit-384-465641.htm
City:[US] 
Location:
 
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