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Human IDO1 Cell-Based Assay Kit |
Create: 07/23/2018 |
Expired Date: | never |
Category: | Diagnostic equipment [Health&Medical&Pharmaceutical] |
Message: | L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of LTrp that have immunosuppressive functions. Indoleamine 2,3-dioxygenases (IDO1 & IDO2), two of the rate limiting enzymes in this pathway, are upregulated in many tumors, providing cancer cells with an avenue for immune evasion. https://www.creativebiomart.net/human-ido1-cell-based-assay-kit-465639.htm |
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City: | Shirley[US]
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Location: |
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