Message: | A QuantiZyme Assay System. The MMP-7 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-7 (MMP-7, matrilysin) using a quenched fluorogenic peptide: OMNIMMP fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP-7, a potential therapeutic target. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH)3, and a detailed instruction booklet.
https://www.creativebiomart.net/matrix-metalloproteinase-7-mmp-7-fluorometric-drug-discovery-kit-463360.htm |