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F2RL1 Activated GPCR Internalization Assay Kit

Create: 10/12/2018
Expired Date:never
Category: Diagnostic equipment [Health&Medical&Pharmaceutical]
Message:Activated GPCR Internalization cells are engineered to co-an untagged GPCR, Enzyme Acceptor (EA) tagged β-Arrestin, and a ProLink (PK) tag localized to the endosomes. Activation of the GPCR induces β-Arrestin recruitment, followed by internalization of the Receptor/Arrestin-EA complex in PK-tagged endosomes. This forces complementation of the two β-galactosidase enzyme fragments (EA and PK), forming functional enzyme that hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance. https://www.creativebiomart.net/f2rl1-activated-gpcr-internalization-assay-kit-462827.htm
City:[US] 
Location:
 
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