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Kv1.1 potassium channel peptide |
| Create: 01/24/2019 |
| Expired Date: | never |
| Category: | Medical testing [Health&Medical&Pharmaceutical] |
| Message: | This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]. https://www.creative-diagnostics.com/Kv1-1-potassium-channel-peptide-177379-427.htm. |
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| City: | Shirley[US]
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| Location: |
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