Kv1.1 potassium channel peptide

Create: 01/24/2019

Expired Date:	never
Category:	Medical testing [Health&Medical&Pharmaceutical]
Message:	This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]. https://www.creative-diagnostics.com/Kv1-1-potassium-channel-peptide-177379-427.htm.






City:	Shirley[US]
Location:

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